Divisions

The Mississippi River can be divided into three sections: the Upper Mississippi, the river from its headwaters to the confluence with the Missouri River; the Middle Mississippi, which is downriver from the Missouri to the Ohio River; and the Lower Mississippi, which flows from the Ohio to the Gulf of Mexico.

Upper Mississippi

The Upper Mississippi runs from its headwaters to its confluence with the Missouri River at St. Louis, Missouri. It is divided into two sections:

1. The headwaters, 493 miles (793 km) from the source to Saint Anthony Falls in Minneapolis, Minnesota; and
2. A navigable channel, formed by a series of man-made lakes between Minneapolis and St. Louis, Missouri, some 664 miles (1,069 km).

The source of the Upper Mississippi branch is traditionally accepted as Lake Itasca, 1,475 feet (450 m) above sea level in Itasca State Park in Clearwater County, Minnesota. The name Itasca was chosen to designate the "true head" of the Mississippi River as a combination of the last four letters of the Latin word for truth (veritas) and the first two letters of the Latin word for head (caput). However, the lake is in turn fed by a number of smaller streams.

From its origin at Lake Itasca to St. Louis, Missouri, the waterway's flow is moderated by 43 dams. Fourteen of these dams are located above Minneapolis in the headwaters region and serve multiple purposes, including power generation and recreation. The remaining 29 dams, beginning in downtown Minneapolis, all contain locks and were constructed to improve commercial navigation of the upper river. Taken as a whole, these 43 dams significantly shape the geography and influence the ecology of the upper river. Beginning just below Saint Paul, Minnesota, and continuing throughout the upper and lower river, the Mississippi is further controlled by thousands of Wing Dikes that moderate the river's flow in order to maintain an open navigation channel and prevent the river from eroding its banks.

The head of navigation on the Mississippi is the Coon Rapids Dam in Coon Rapids, Minnesota. Before it was built in 1913, steamboats could occasionally go upstream as far as Saint Cloud, Minnesota, depending on river conditions.

The uppermost lock and dam on the Upper Mississippi River is the Upper St. Anthony Falls Lock and Dam in Minneapolis. Above the dam, the river's elevation is 799 feet (244 m). Below the dam, the river's elevation is 750 feet (230 m). This 49-foot (15 m) drop is the largest of all the Mississippi River locks and dams. The origin of the dramatic drop is a waterfall preserved adjacent to the lock under an apron of concrete. Saint Anthony Falls is the only true waterfall on the entire Mississippi River. The water elevation continues to drop steeply as it passes through the gorge carved by the waterfall.

After the completion of the St. Anthony Falls Lock and Dam in 1963, the river's head of navigation moved upstream, to the Coon Rapids Dam. However, the Locks were closed in 2015 to control the spread of invasive Asian carp, making Minneapolis once again the site of the head of navigation of the river.

The Upper Mississippi has a number of natural and artificial lakes, with its widest point being Lake Winnibigoshish, near Grand Rapids, Minnesota, over 11 miles (18 km) across. Lake Onalaska, created by Lock and Dam No. 7, near La Crosse, Wisconsin, is more than 4 miles (6.4 km) wide. Lake Pepin, a natural lake formed behind the delta of the Chippewa River of Wisconsin as it enters the Upper Mississippi, is more than 2 miles (3.2 km) wide.

By the time the Upper Mississippi reaches Saint Paul, Minnesota, below Lock and Dam No. 1, it has dropped more than half its original elevation and is 687 feet (209 m) above sea level. From St. Paul to St. Louis, Missouri, the river elevation falls much more slowly, and is controlled and managed as a series of pools created by 26 locks and dams.

The Upper Mississippi River is joined by the Minnesota River at Fort Snelling in the Twin Cities; the St. Croix River near Prescott, Wisconsin; the Cannon River near Red Wing, Minnesota; the Zumbro River at Wabasha, Minnesota; the Black, La Crosse, and Root rivers in La Crosse, Wisconsin; the Wisconsin River at Prairie du Chien, Wisconsin; the Rock River at the Quad Cities; the Iowa River near Wapello, Iowa; the Skunk River south of Burlington, Iowa; and the Des Moines River at Keokuk, Iowa. Other major tributaries of the Upper Mississippi include the Crow River in Minnesota, the Chippewa River in Wisconsin, the Maquoketa River and the Wapsipinicon River in Iowa, and the Illinois River in Illinois.

The Upper Mississippi is largely a multi-thread stream with many bars and islands. From its confluence with the St. Croix River downstream to Dubuque, Iowa, the river is entrenched, with high bedrock bluffs lying on either side. The height of these bluffs decreases to the south of Dubuque, though they are still significant through Savanna, Illinois. This topography contrasts strongly with the Lower Mississippi, which is a meandering river in a broad, flat area, only rarely flowing alongside a bluff (as at Vicksburg, Mississippi).

Middle Mississippi

The Mississippi River is known as the Middle Mississippi from the Upper Mississippi River's confluence with the Missouri River at St. Louis, Missouri, for 190 miles (310 km) to its confluence with the Ohio River at Cairo, Illinois.

The Middle Mississippi is relatively free-flowing. From St. Louis to the Ohio River confluence, the Middle Mississippi falls 220 feet (67 m) over 180 miles (290 km) for an average rate of 1.2 feet per mile (23 cm/km). At its confluence with the Ohio River, the Middle Mississippi is 315 feet (96 m) above sea level. Apart from the Missouri and Meramec rivers of Missouri and the Kaskaskia River of Illinois, no major tributaries enter the Middle Mississippi River.

Lower Mississippi

The Mississippi River is called the Lower Mississippi River from its confluence with the Ohio River to its mouth at the Gulf of Mexico, a distance of about 1,000 miles (1,600 km). At the confluence of the Ohio and the Middle Mississippi, the long-term mean discharge of the Ohio at Cairo, Illinois is 281,500 cubic feet per second (7,970 cubic meters per second), while the long-term mean discharge of the Mississippi at Thebes, Illinois (just upriver from Cairo) is 208,200 cu ft/s (5,900 m3/s). Thus, by volume, the main branch of the Mississippi River system at Cairo can be considered to be the Ohio River (and the Allegheny River further upstream), rather than the Middle Mississippi.

In addition to the Ohio River, the major tributaries of the Lower Mississippi River are the White River, flowing in at the White River National Wildlife Refuge in east central Arkansas; the Arkansas River, joining the Mississippi at Arkansas Post; the Big Black River in Mississippi; and the Yazoo River, meeting the Mississippi at Vicksburg, Mississippi. The widest point of the Mississippi River is in the Lower Mississippi portion where it exceeds 1 mile (1.6 km) in width in several places.

Deliberate water diversion at the Old River Control Structure in Louisiana allows the Atchafalaya River in Louisiana to be a major distributary of the Mississippi River, with 30% of the combined flow of the Mississippi and Red Rivers flowing to the Gulf of Mexico by this route, rather than continuing down the Mississippi's current channel past Baton Rouge and New Orleans on a longer route to the Gulf. Although the Red River is commonly mistaken for an additional tributary, its water flows separately into the Gulf of Mexico through the Atchafalaya River.